At-Bristol ran two XploreHealth events for four school groups earlier this term on the theme of drug development.
Wootten Bassett School (15)
The Woodroffe School (11)
Haberdashers Monmouth School for Girls (15)
Redland Green School (18)
The students took part in the ‘How are medicines developed?’ practical investigation which began with a brief introduction to the development and research of new medicines. The practical investigation was carried out in three stages:
Stage 1: Synthesis of a new molecule to be used in the treatment of Parkinson's
Stage 2: Isolation of the product by filtration
Stage 3: Characterisation of the product through chromatography
Between stages 2 and 3 students discussed how the new synthesised molecule could potentially benefit Parkinson's patients.
Results from the chromatography were disappointing on both days. The original product never appeared under the ultra violet light. Despite this the practical investigation and application to real world science was a beneficial experience for the students and good feedback was received.
The students also took part in a discussion activity regarding access to treatment. This is a simple continuum activity where students decide if they agree or disagree with statements relating to treatment options and access.